皮质类固醇类药物(通常是应用地塞米松)对各种类型的脑水肿常被应用,但其显著效果仅限于肿块伴有脑水肿的病变。例如,类固醇类药物曾被用为脑性疟疾的救命药物,但最近通过Warrell等的双盲试验证实,不仅无益反而使昏迷期延长,并易发生肺炎,而且明显增加胃肠道出血。 Corticosteroids (usually dexamethasone) are often used for various types of brain edema, but their significant effect is limited to those with lumps associated with brain edema. For example, steroid drugs have been used as lifesaving drugs for cerebral malaria, but the recent double-blind trial by Warrell et al. Confirmed that it was not only not beneficial but rather prolonged the period of coma and caused pneumonia and markedly increased gastrointestinal bleeding.