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目的探讨复发性脑梗塞与抗心磷脂抗体、血脂的关系。方法采用酶联免疫吸附(ELISA)等方法检测了37例复发性脑梗塞(RCI)和68例首发性脑梗塞(FCI)患者的血清抗心磷脂抗体(ACLA)及血脂7项指标,并与50例对照组比较。结果RCI组的ACLA阳性率明显高于FCI及对照组;TG、TC、LDL-c及APOB血清平均水平RCI和FCI组均明显高于对照组,而血脂水平两组比较差异无统计学意义。结论ACLA与RCI的发生有密切关系,血脂代谢对RCI和FCI的影响无差别。
Objective To investigate the relationship between recurrent cerebral infarction and anticardiolipin antibodies and blood lipids. Methods Serum anti-cardiolipin antibodies (ACLA) and serum lipids were measured in 37 patients with recurrent cerebral infarction (RCI) and 68 patients with first cerebral infarction (FCI) by enzyme-linked immunosorbent assay (ELISA) 50 cases of control group comparison. Results The positive rate of ACLA in RCI group was significantly higher than that in FCI group and control group. The serum levels of TG, TC, LDL-c and APOB in RCI group were significantly higher than those in control group, but there was no significant difference between the two groups. Conclusion ACLA is closely related to the occurrence of RCI. There is no difference between RCA and FCI in blood lipid metabolism.