呋喃西林为一种新的杀菌与抑菌药物,近来国内临床上使用较为广泛,关于治疗反应国内尚无报导,现将我院应用呋喃西林治疗泌尿道感染中所发生的毒性反应报道如下:病例介绍【例1】患儿周某,病案号183193, 女,11岁,因反复发作之尿痛、尿急已一年,于1959年5月21日入院。经检查诊断为左侧肾盂积水及慢性肾盂肾炎。小便内蛋白(+),有较多之白血球,小便培养有大肠杆菌及绿脓杆菌。于8月4日开始应用呋喃西林,每次口服50毫克,一日三次。治行约三周后,两侧手与脚呈麻木与庠感,而侧腕、踝、指、趾关节疼痛。检查上下肢的知觉,运动及反射 Nitrofurazone as a new bactericidal and antibacterial drugs, the recent domestic clinical use is more extensive, there is no report on the response to treatment in our hospital now apply nitrofurazone treatment of urinary tract infections in toxic reactions reported as follows: [Case Description Case 1] Children Zhou, medical record number 183193, female, 11 years old, due to recurrent dysuria, urinary urgency has been one year, on May 21, 1959 admission. After examination, diagnosed as left hydronephrosis and chronic pyelonephritis. Urine protein (+), there are more white blood cells, urinary culture Escherichia coli and Pseudomonas aeruginosa. Nitrofurazone was started on August 4, 50 mg orally each time, three times a day. After about three weeks’ treatment, the hands and feet on both sides are numb and sore, while the pain on the wrist, ankle, finger and toe joints. Check the sensory, motor and reflexes of upper and lower limbs