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目的探讨复发性胶质瘤患者再手术的效果。方法对22例复发性胶质瘤患者再手术前的功能状态、两次手术间隔时间及手术切除的程度与术后存活期等资料进行临床和统计学分析。结果第二次手术前生活能自理或半自理的病人(Kamofsky计分≥60)平均生存期约16月,生活不能自理的病人(Karnofsky计分<60)平均生存期约6月(P<0.01)。两次手术间隔时间大于1年者平均生存期约17月,间隔时间小于半年者平均生存期约6月(P<0.01)。手术肿瘤全切除者平均生存期约15月,次全切除者平均生存期约10月(P<0.05)。结论术前功能情况好,手术间隔时间大于1年及术中全切肿瘤者再手术治疗可获得较好效果。
Objective To investigate the effect of reoperation in patients with recurrent glioma. Methods 22 cases of recurrent glioma patients before reoperation functional status, two surgical intervals and the degree of surgical resection and postoperative survival and other data for clinical and statistical analysis. Results The mean survival time was about 16 months in patients who were able to take care of themselves or semi-self-care before the second surgery (Kamofsky score ≥60) and about 6 months in patients who were unable to take care of themselves (Karnofsky score <60) ). The average survival time of two operations more than 1 year was about 17 months, and the interval time was less than the average survival time of about 6 months (P <0.01). The average survival time of total resection of surgical tumor was about 15 months, and the average survival time of subtotal resection was about 10 months (P <0.05). Conclusion The preoperative function is good, the operative interval is longer than 1 year and the total resection of the tumor can be reoperated well.