如何选择敏感性强的化疗方案是临床医生关注的课题。如能建立一个有效的体外预测方法,将有利于进一步提高疗效。本文应用大肠癌原代培养技术对52例大肠癌在不同浓度5-Fu条件下培育,观察其细胞生长受抑制情况与对照组比较,评价该细胞对5-Fu的敏感程度,预测该大肠癌对5-Fu的敏感性,以期有助于临床选择治疗方案。现将方法及结果报道如下。 How to select a sensitive chemotherapy regimen is a topic of concern for clinicians. If we can establish an effective in vitro prediction method, it will help to further improve the efficacy. This article uses the primary culture of colorectal cancer to 52 cases of colorectal cancer in different concentrations of 5-Fu conditions, observe its inhibition of cell growth compared with the control group, evaluate the sensitivity of the cell to 5-Fu, predict the colorectal cancer Sensitivity to 5-Fu in order to help the clinical choice of treatment options. The method and results are reported below.