从青藤科植物黑吹风(Illigera sp)总生物碱中分离出一个单体,经化学鉴定命名为放线瑞香宁碱(actinodapbnine简称Ac)。分子式C_(18)H_(17)NO_4,为10-甲氧基-1,2-(次甲二氧基)-6-去甲阿朴菲-9-醇(图1)。动物实验表明,Ac具有解痉、镇痛、局麻及降低小鼠体温等作用,并证明其镇痛作用系非中枢性。本文进一步研究其镇痛作用和对不同动物正常 A monomer was isolated from the total alkaloid of Illigera sp., Which was chemically identified as actinodapbnine (Ac). The molecular formula C_ (18) H_ (17) NO_4 is 10-methoxy-1,2-methyphenylenedioxy-6-norpafio-9-ol (Figure 1). Animal experiments show that Ac has antispasmodic, analgesic, local anesthesia and reduce the role of body temperature in mice, and to prove that its analgesic effect of non-central. This article further studies its analgesic effect and normalization on different animals