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作者最近意外观察到 ,服用华法林 (Ｗａｒ ｆａｒｉｎ)开始剂量 5ｍｇ(接近于平均维持量 )至第 4～ 5日可见其抗凝治疗效果至少与 1 0ｍｇ负荷剂量相同。本文用随机对比方法证实这一发现。对象和方法 选择在华法林开始服用时期国际正常化比 (ＩＮＲ)目标意欲到 2 0～ 3 0的患
The authors recently unexpectedly observed that the warfarin dose was at least as good as the 10-mg loading dose with warfarin starting at doses of 5 mg (approaching the mean maintenance dose) until days 4 through 5. This article uses a randomized comparison to confirm this finding. Subjects and methodological options to start taking warfarin period International normalized ratio (INR) target is intended to 20 ~ 30 patients