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目的观察芪黄汤结合瑞格列奈治疗早期糖尿病肾病的临床疗效。方法将120例早期糖尿病肾病患者随机分成两组,对照组采用瑞格列奈治疗,治疗组采用芪黄汤结合瑞格列奈治疗。比较两组患者临床疗效以及治疗前后肾功能指标水平。结果治疗组总有效率明显高于对照组(P<0.05);治疗后,两组患者的各项肾功能指标水平均下降,而治疗组患者的下降幅度更为显著(P<0.01)。结论相比单纯瑞格列奈治疗,采用芪黄汤结合瑞格列奈治疗早期糖尿病肾病的临床疗效更为显著,同时更为有效地改善肾功能。
Objective To observe the clinical efficacy of Qhuang Decoction combined with repaglinide in the treatment of early diabetic nephropathy. Methods 120 patients with early diabetic nephropathy were randomly divided into two groups. The control group was treated with repaglinide. The treatment group was treated with Qihuang Decoction combined with repaglinide. The clinical efficacy and the level of renal function before and after treatment were compared between the two groups. Results The total effective rate in the treatment group was significantly higher than that in the control group (P <0.05). After treatment, the levels of renal function indexes decreased in both groups, but the reduction rate in the treatment group was more significant (P <0.01). Conclusion Compared with the simple repaglinide treatment, the treatment of early diabetic nephropathy with Qhuang Decoction combined with repaglinide is more effective in clinical treatment, while more effective in improving renal function.