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目的探讨重金属中毒病人尿中β2微球蛋白(β2MG)、视黄醇结合蛋白(RBP)之间相关性。方法回顾分析本院收治73例重金属中毒病例的尿β2MG、RBP同时升高的资料,用SPSS17.0对其进行了直线相关性分析。结果 73例中毒病例,尿镉高者占76.7%,镉中毒者占6.8%,镉观察对象占2.7%,铅中毒者占9.7%,砷中毒者占4.1%;尿β2MG与RBP之间r=-0.018(P>0.05);RBP女性高于男性(P<0.05)。结论尿β2MG、RBP在镉超标中常见,但不具有直线相关性。
Objective To investigate the correlation between urine β2 microglobulin (β2MG) and retinol binding protein (RBP) in patients with heavy metal poisoning. Methods A retrospective analysis of 73 patients with heavy metal poisoning in our hospital urinary β2MG, RBP elevated at the same time, using SPSS17.0 linear correlation analysis. Results Among the 73 poisoning cases, 76.7% were urinary cadmium, 6.8% were cadmium poisoning, 2.7% were cadmium, 9.7% were lead poisoning and 4.1% were arsenic poisoning. Urinary β2MG and RBP were r = -0.018 (P> 0.05). RBP women were higher than men (P <0.05). Conclusion Urinary β2MG and RBP are common in cadmium overload, but not in a linear correlation.