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目的 探讨双相障碍患者焦虑症状的社会人口学及临床特征方面的危险因素.方法 对2010年9月1日至2011年2月28日“中国双相情感障碍患者诊断评估服务”研究项目的数据进行二次分析,306例双相障碍患者根据是否伴有焦虑症状,分为伴焦虑症状组(200例),和不伴焦虑症状组(106例).通过Logistic回归分析探讨双相障碍患者焦虑症状的相关危险因素.结果 与不伴焦虑症状组相比,伴焦虑症状组年龄偏小[(35.10±11.09)岁]、首次发病年龄小[(27.93±10.04)岁]、男性多见(t=4.603,P＜0.05)、平均既往发病次数多[(3.21±3.77)次]、发作频繁(t=17.328,P＜0.05)、有诱因起病(t=14.859,P＜0.05)、发作有周期性或季节性(t=8.300,P＜0.05)特点.Logistic回归分析显示,有诱因起病(OR=2.315)、发作频繁(OR=10.852)与双相障碍焦虑症状的危险因素相关(P＜0.05).结论 有诱因起病、发作频繁可能是双相障碍焦虑症状的危险因素.“,”Objective To analyze the risk factors of socio-demographic and clinical characteristics related to anxious symptoms in bipolar depression patients(BDP).Methods This was a secondary analysis of data from the Diagnostic Assessment Service for People with Bipolar Depression in China(DASP)from September 1,2010 to February 28,2011.According to the criterion that comorbid anxiety or not, BDP(n=306)were divided into comorbid anxiety group(n =200)(65.4％)and without anxiety group(n =106)(34.6％).Further analysis for risk factors of anxious symptoms in BDP was performed by the multivariate logistic regression analysis.Results BDP with anxiety were younger(35.10± 11.09), younger at illness onset(27.93-± 10.04), ruore male(t =4.603, P＜0.05), more lifetime episodes(3.21 ± 3.77), frequently episodes(t =17.328,P＜0.05),inducement onset(t=14.859,P＜0.05)and more seasonal episodes(t=8.300,P＜0.05)compared with BDP without anxiety.Logistic regression analysis showed that inducement onset(OR=5.023)and episodes frequency(OR=10.852)was significantly associated with anxious symptom(P＜0.05).Conclusion The finding indicates that postpartum onset and depressive episodes frequency may be risk factors of bipolar depression with anxiety.