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目的观察盐酸法舒地尔对心房纤颤合并脑栓塞患者的临床疗效。方法选择94例心房纤颤合并脑栓塞的患者随机分为治疗组52例,对照组42例,两组一般资料具有可比性(P>0.05)。对照组给予低分子肝素钠4000U皮下注射,共7d;治疗组在对照组基础上加用0.9%氯化钠溶液100ml+盐酸法舒地尔30mg,12h1次。结果治疗组总有效率为89.6%,对照组总有效率为71.4%。结论盐酸法舒地尔对心房颤动合并脑栓塞患者具有显著神经保护和治疗作用,可减少致残率。
Objective To observe the clinical efficacy of fasudil hydrochloride in patients with atrial fibrillation and cerebral embolism. Methods A total of 94 patients with atrial fibrillation and cerebral embolism were randomly divided into treatment group (n = 52) and control group (n = 42). The general data of two groups were comparable (P> 0.05). Control group was given low molecular weight heparin 4000U subcutaneous injection, a total of 7d; the treatment group on the basis of the control group plus 0.9% sodium chloride solution 100ml fasudil hydrochloride 30mg, 12h1 times. Results The total effective rate was 89.6% in the treatment group and 71.4% in the control group. Conclusion Fasudil hydrochloride has significant neuroprotective and therapeutic effects on patients with atrial fibrillation complicated with cerebral embolism, and can reduce the morbidity.