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作者为了探讨急性心肌梗塞初期尿激酶快速大量静脉内(IV)给药的有效性,与冠状动脉内(PTCR)给药作了对比研究。作者的研究对象是发病6小时以内的急性心肌梗塞患者51例共分三组(lV组13例、PTCR 组33例、lV+PTCR组:5例)。Ⅳ法:尿激酶98～192(平均163)万单位,于10～30(平均19)分钟内快速静脉注射。随后进行冠状动脉造影,对仍有冠状动脉栓塞的病例再行PTCR 给药。PTCR 法:尿激酶2万单位/分,冠状动脉持续注入.
In order to investigate the efficacy of fast, bulk intravenous (IV) administration of urokinase at the initial stage of acute myocardial infarction, we compared it with intracoronary (PTCR) administration. The study was performed in 51 patients with acute myocardial infarction within 6 hours of onset (13 in the lV group, 33 in the PTCR group and 5 in the lV + PTCR group). Ⅳ method: urokinase 98 ~ 192 (average 163) million units, in 10 to 30 (average 19) minutes rapid intravenous injection. Coronary angiography was subsequently performed and PTCR was administered to patients who still had coronary embolism. PTCR method: urokinase 20,000 units / min, continuous coronary injection.