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目的探讨直肠类癌的临床病理特点及影响预后的因素。方法回顾性分析31例直肠类癌患者的临床资料,所有病例均经手术和病理检查证实。将其按肿瘤直径大小和肌层是否有浸润分别分组,比较不同肿瘤直径各组和肌层是否浸润各组的手术治疗效果。结果本组31例直肠类癌患者的中位年龄49岁(22～83岁),中位随访时间36个月(15～86个月),随访率为80.6%(25/31)。随访期内,肿瘤直径≤l.0 cm的15例手术切除肿瘤后无复发,直径1.0～2.0 cm的7例中复发1例,直径>2.0 cm的3例中2例因类癌肝转移死亡。直肠类癌是否浸润肌层或全层以及是否有转移均与肿瘤大小有关(P<0.05);肿瘤的浸润深度与转移有关(P<0.05)。随着直肠类癌直径的增大,肿瘤浸润深度加深,转移发生率增高。结论直肠类癌的大小和肌层浸润可能是影响患者生存的重要因素,是选择手术方式时需参考的重要依据。
Objective To investigate the clinicopathological features and prognostic factors of rectal carcinoids. Methods Retrospective analysis of 31 cases of rectal carcinoid patients clinical data, all cases were confirmed by surgery and pathology. According to the size of the tumor and the presence or absence of myometrial invasion were grouped, comparing the different tumor diameters and muscle layers of each group infiltration of the surgical treatment effect. Results The median age of patients with rectal carcinoid in this group was 49 years (22-83 years). The median follow-up time was 36 months (range, 15-86 months). The follow-up rate was 80.6% (25/31). During the follow-up period, no recurrence was found in 15 cases with tumors ≤1.0 cm in diameter. One case recurred in 7 cases with 1.0 ~ 2.0 cm in diameter, and 2 cases died of carcinoid liver metastases in 3 cases with diameter> 2.0 cm . Rectal carcinoid invasion of myometrium or full-thickness and whether the metastasis were related to tumor size (P <0.05). The depth of invasion was related to metastasis (P <0.05). With the increase of rectal carcinoid diameter, the depth of tumor invasion deepens and the incidence of metastasis increases. Conclusion Rectal carcinoid size and myometrial invasion may be an important factor affecting the survival of patients is an important basis for the selection of surgical methods need to be referenced.