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目的：探讨中药配合腹膜透析（腹透）治疗狼疮肾炎尿毒症患者的疗效。方法：随机设置３７例中西医结合治疗组（治疗组）与３５例对照组，２组均采用连续不卧床腹透及激素标准疗程治疗。治疗组并加用中药治疗。结果：治疗半年后治疗组完全缓解率３５．１％，复发率８．１％，不良反应率３７．８％，脱离透析率８１．１％；对照组分别为１４．２％、２２．９％、７４．３％和４５．７％。治疗组总蛋白（ＴＰ）、血红蛋白（Ｈｂ）均较对照组明显升高〔（６８．３±３．９）ｇ／Ｌ比（５７．９±４．２）ｇ／Ｌ，（８１．３±９．９）ｇ／Ｌ比（７２．１±６．３）ｇ／Ｌ〕，Ｐ均＜０．０５；血尿素氮（ＢＵＮ）、血肌酐（ＳＣｒ）和尿蛋白均明显降低〔分别为（１６．１±７．５）ｍｍｏｌ／Ｌ比（２４．５±９．６）ｍｍｏｌ／Ｌ，（２６９．３±８７．３）μｍｏｌ／Ｌ比（４５７．０±９３．５）μｍｏｌ／Ｌ，（０．６±４．９）ｇ／２４ｈ比（３．５±５．７）ｇ／２４ｈ〕，Ｐ均＜０．０５。结论：中药配合腹透治疗狼疮肾炎尿毒症优于单纯西医治疗。
Objective: To investigate the curative effect of traditional Chinese medicine combined with peritoneal dialysis (peritoneal dialysis) in the treatment of uremic patients with lupus nephritis. Methods: A total of 37 cases of Integrative Chinese and Western medicine (treatment group) and 35 cases of control group were randomly allocated. Both groups were treated by continuous ambulatory peritoneal dialysis and hormone therapy. Treatment group and add traditional Chinese medicine treatment. Results: After six months of treatment, the complete remission rate was 35.1%, the recurrence rate was 8.1%, the rate of adverse reactions was 37.8% and the rate of dialysis was 81.1%. The control group was 14.2% and 22.9 %, 74.3% and 45.7%. The total protein (TP) and hemoglobin (Hb) in the treatment group were significantly higher than those in the control group [(68.3 ± 3.9) g / L vs 57.9 ± 4.2 ± 9.9) g / L (72.1 ± 6.3) g / L, all P <0.05; BUN, SCr and urinary protein were significantly decreased 〔 (16.1 ± 7.5) mmol / L (24.5 ± 9.6) mmol / L, (269.3 ± 87.3) μmol / L vs 457.0 ± 93.5 μmol (0.6 ± 4.9) g / 24hh (3.5 ± 5.7) g / 24h〕, P <0.05. Conclusion: Chinese medicine combined with peritoneal dialysis treatment of lupus nephritis uremia is better than Western medicine alone.