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目的比较酒石酸双氢可待因和磷酸可待因治疗中度癌痛的疗效和不良反应。方法采用随机双盲对照研究的方法,对69例有中度癌痛的肿瘤病人用酒石酸双氢可待因和磷酸可待因进行治疗,观察疗效和不良反应。结果双氢可待因与磷酸可待因用于中度癌痛患瘏,两者在镇痛强度上无显著差异,不良反应与其他阿片类药物类似。结论酒石酸双氢可待因和磷酸可待因可用于治疗中度癌痛。
Objective To compare the efficacy and side effects of codeine dihydrocartilate and codeine phosphate in the treatment of moderate cancer pain. Methods A randomized, double-blind controlled study was conducted on 69 patients with moderate cancer pain treated with dihydrocodeine tartrate and codeine phosphate to observe the curative effect and adverse reaction. Results Both hydrocodone and codeine phosphate were used in patients with moderate cancer pain. There was no significant difference in analgesic strength between the two drugs. Adverse reactions were similar to other opioids. Conclusions Dihydrocodeine tartrate and codeine phosphate are useful in the treatment of moderate cancer pain.