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饮水经氯消毒时会产生三氯甲烷等化学物。目前国内对三氯甲烷的致畸效应和致癌作用已作了不少研究,但对其致突变作用探讨较少。本试验初步观察了三氯甲烷对小鼠骨髓微核形成的影响,结果如下: 1.动物:NIH纯种雄性小鼠,体重20~25g,10~12周龄,按5只一组,随机分成14组。 2.:三氯甲烷(AR),进口分装,由广州医药站化学试剂公司分装。 3.实验方法:用食用菜籽油作溶剂,将三氯甲
Chlorination of drinking water when chlorine will produce chemicals such as chloroform. At present, many studies have been done on the teratogenic effects and carcinogenic effects of chloroform in China, but there are few studies on their mutagenic effects. The experiment initially observed the impact of trichloromethane on the formation of micronuclei in mouse bone marrow, the results are as follows: 1. Animals: NIH purebred male mice, weighing 20 ~ 25g, 10 to 12 weeks of age, according to a group of 5 randomized Divided into 14 groups. 2 .: Trichloromethane (AR), imported and repackaged, divided by the Guangzhou Medical Station Chemical Reagent Company. 3. Experimental methods: edible rapeseed oil as a solvent, trichloromethane