新生儿应激性溃疡是危重疾病的严重并发症,以上消化道出血为主要表现,常见于休克、颅内出血、败血症等危重症,病死率高。笔者医院自2000年9月-2002年12月应用西咪替丁预防新生儿应激性上消化道出血20例,取得了满意疗效,现总结如下。1临床资料1.1病例选择根据《实用儿科学》第6版诊断标准,20例患儿均排除维生素K依赖因子缺乏症;通过呕吐物碱变性试验(Apt试验)排除咽血综合征;通过检查鼻咽、口腔有 Neonatal stress ulcer is a serious complication of critical illness, the above gastrointestinal bleeding as the main performance, common in shock, intracranial hemorrhage, sepsis and other critical illness, high mortality. The author hospital from September 2000 to December 2002 application of cimetidine to prevent neonatal stress induced upper gastrointestinal bleeding in 20 cases, and achieved satisfactory results, are summarized as follows. 1 Clinical data 1.1 Case Selection According to the “Practical Pediatrics,” the 6th edition of the diagnostic criteria, 20 patients were excluded vitamin K-dependent deficiency; vomit alkalosis test (Apt test) to exclude throat syndrome; by examining the nose Pharynx, oral there