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目的:分析艾滋病合并肺部感染病例各种实验室检测指标及其关系,以指导临床早期诊断及治疗。方法:整理120例临床诊断艾滋病合并肺部感染病例资料,分析其血液HIV载量、CD 4+T淋巴细胞含量、微生物感染病原谱及药敏情况。结果:随CD4+T淋巴细胞含量的下降,血液HIV载量升高,其肺部感染发生频率提高,以大肠埃希菌、铜绿假单胞菌、结核杆菌居前3位,并检出多种人体正常寄居菌,细菌耐药率较高。结论:艾滋病合并肺部感染病例由于自身免疫力下降,感染病原体多样,人体常见寄居菌感染机会增加,抗感染治疗时应合理用药,防止多重感染发生。
Objective: To analyze various laboratory test indicators and their relationship in cases of AIDS complicated with pulmonary infection in order to guide clinical early diagnosis and treatment. Methods: Data of 120 cases of clinically diagnosed AIDS complicated with pulmonary infection were collected and analyzed for HIV blood load, CD 4 + T lymphocyte content, pathogenicity of microbial infection and drug susceptibility. Results: With the decrease of CD4 + T lymphocyte, HIV infection increased with the increase of blood HIV infection. The frequency of pulmonary infection increased with the increase of CD4 + T lymphocyte count. Among them, Escherichia coli, Pseudomonas aeruginosa and Mycobacterium tuberculosis were among the top three Normal species of human dysenteria, bacterial resistance rate higher. Conclusions: Due to the decline of autoimmune immunity and the multiplicity of infectious pathogens in AIDS-associated pulmonary infections, the chances of human infection with common resident germs increase. Anti-infective therapy should be used rationally to prevent multiple infections.