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60～85岁胃癌切除的36人为研究对象,术前肝、肾功能正常,术中持续静注前列腺素E_1(PGE_1),并与未用PGE_1者对比,评价术后肝、肾功能。两组各18人,其中胃次全切术13人、胃全切术5人。除外既往有肝疾患病史、合并胆囊摘除、肝部分切除及肝动脉结扎病例。手术前晚21:00时口服三唑仑0.125～0.25mg和克塞平75mg,手术麻醉前90min口服地西泮10mg及克塞平75mg。用硫喷妥、丁二酰胆碱麻醉,用异戊二烯+笑气+氧气维持麻
Thirty-six patients with 60 to 85 years old gastric cancer resection were studied. Preoperative liver and renal function were normal. Prostaglandin E1 (PGE_1) was continuously injected intravenously during the operation and compared with those without PGE_1 to evaluate postoperative liver and renal function. There were 18 patients in each group, including 13 patients undergoing total gastrectomy and 5 patients undergoing total gastrectomy. Except for previous history of liver disease, gallbladder removal, partial hepatectomy, and hepatic artery ligation. Oral triazolam 0.125 to 0.25 mg and kesaiping 75 mg were administered orally at 21:00 hours before surgery, and 10 mg of diazepam and 75 mg of colcesil were administered orally 90 min before surgery. With thiopental, succinylcholine anesthesia, isoprene + laughing gas + oxygen to maintain hemp