在糖尿病时 ,由于血糖升高 ,使葡萄糖和血浆中蛋白质发生非酶糖化 ,最终形成糖基化终末产物 (ＡＧＥ) ,糖基化了蛋白质可发生结构、机械强度、溶解性、配位结合、交联等改变 ,糖尿病的各种慢性并发症都与糖尿病的蛋白质糖基化密切相关 ,可是血管病变的病理基础。所以采取有效的 In diabetes mellitus, glucose and plasma proteins undergo non-enzymatic glycation as a result of elevated blood glucose, eventually forming a glycosylation end product (AGE) that can undergo structural, mechanical strength, solubility, coordination binding , Cross-linking and other changes, a variety of chronic complications of diabetes are closely related to diabetes and protein glycosylation, but the pathological basis of vascular lesions. So take effective