患者,男,61岁。前胸部皮肤慢性、进行性暗褐色色素沉着,伴皮肤毛细血管扩张和纤维样变6个月。之前患者已确诊为肺癌(腺癌)脑转移(图1),分型及分期为cT2aN3M1,stageIV。皮损主要局限在颈前及前胸部,形状不规则,质略硬,皮温不高,无结节、渗出等(图2)。皮损组织活检显示:真皮弥 Patient, male, 61 years old. Chronic front chest skin, progressive dark brown pigmentation, with telangiectasia and fibrosis of the skin for 6 months. Prior to the patient has been diagnosed as lung cancer (adenocarcinoma) brain metastases (Figure 1), type and stage of cT2aN3M1, stageIV. Skin lesions are mainly confined to the anterior and thoracic trocars, irregular in shape, hard in quality, low in dermal temperature, without nodules, exudation, etc. (Figure 2). Skin lesions Biopsy shows: Mi Mi