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山东省临沂市肿瘤医院范士怀等开展的“第二掌骨侧疗法缓解顽固性癌性疼痛的临床研究”于1995年底通过了专家技术鉴定。该项目运用生物全应、理论在人体第二掌骨烧测穴位群上确定相应的全总穴位进行按压和穴位注射，对晚期癌病，尤其是顽同性癌痛病人的治疗取得良好的效果，经1
The clinical study of the second metacarpal side therapy to relieve intractable cancer pain was carried out by Lin Shishi Cancer Hospital of Shandong Province. The project uses bio-improvement theory to determine the corresponding total acupuncture point on the second metacarpal bone burning point of the human body to perform pressing and acupoint injection. It has achieved good results for the treatment of advanced cancer diseases, especially those with persistent cancer pain. 1