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1目的 探讨恶性肿瘤病人血清肿瘤特异性生长因子 (TSGF)的水平及临床意义。 2方法 应用TSGF快速检测试剂盒检测恶性肿瘤病人血清样本中的 TSGF含量。 3结果 恶性肿瘤病人血清中 TSGF含量明显高于健康人和良性肿瘤病人 (t=31.71,2 1.19,P<0 .0 1) ,其检测灵敏度为 83.2 % ,特异度为 92 .0 % .恶性肿瘤病人放、化疗有效者 ,TSGF含量较治疗前明显下降 (t=9.31,P<0 .0 1) ;放、化疗后恶化者 ,TSGF含量较治疗前明显上升 (t=6 .43,P<0 .0 1)。 4结论 TSGF检测具有灵敏度及特异度高等特点 ,有利于恶性肿瘤的诊断 ,对恶性肿瘤病人的病情和预后判断具有重要价值
Objective To investigate the level and clinical significance of serum tumor-specific growth factor (TSGF) in patients with malignant tumors. 2 Methods The serum TSGF levels in patients with malignant tumors were measured using the TSGF rapid test kit. 3 Results Serum levels of TSGF in patients with malignant tumors were significantly higher than those in healthy and benign tumors (t = 31.71, 2 1.19, P < 0.01), with a detection sensitivity of 83.2% and a specificity of 92.0%. In patients with tumors with radiotherapy and chemotherapy, TSGF levels were significantly lower than before treatment (t = 9.31, P < 0.01); after radiotherapy and chemotherapy, the TSGF levels were significantly higher than before treatment (t = 6.43, P). <0. 0 1). 4 Conclusion TSGF detection has the characteristics of high sensitivity and specificity, which is conducive to the diagnosis of malignant tumors and is of great value in the judgment of the condition and prognosis of malignant tumor patients.