免疫过氧化物酶技术在70年代初就已采用,但从单克隆抗体问世以来则更常被使用.原先免疫过氧化物酶技术只用于皮肤病的研究,即对大疱性疾病(如寻常性天疱疮,大疱性类天疱疮,红斑狼疮,妊娠疱疹,疱疹样皮炎和获得性大疱性表皮松解症)中体内结合的免疫球蛋白或补体的定位等.新近,免疫过氧化酶也已用于皮肤病理 Immunoperoxidase has been used since the early 1970s but has been more commonly used since the advent of monoclonal antibodies.Previous immunoperoxidase techniques were used only for the study of dermatoses, Pemphigus vulgaris, bullous pemphigoid, lupus erythematosus, gestation herpes, dermatitis herpetiformis and epidermolysis bullosa acquisita), etc. Recently, the immunization of immune Peroxidase has also been used in the skin pathology