刺芫荽叶中的抗炎镇痛成分

来源 :国外医学(中医中药分册) | 被引量 : 0次 | 上传用户:wcjlb
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研究了刺芫荽(Eryngium foetidum)叶煎剂对啮齿动物的抗炎镇痛作用。药物:煎剂由干燥刺芫荽叶提取.提取率为13.21%,干燥粉末以等渗0.9%氯化钠或乙醇(70%)溶解稀释(备用)。给药剂量按mg生药材量/kg体重计算。动物:雄性Swiss小鼠(20~25g)和雄性Wistar大鼠(200~250g)。抗炎试验有:①角叉菜胶诱导大鼠足水肿:提取物口服给药(250、500和750mg/kg)。用体积计量器分别测定给角叉菜胶前后1、2、3、4和5h的 The anti-inflammatory and analgesic effects of Eryngium foetidum leaf decoction on rodents were studied. Drugs: The decoction was extracted from dried Locust leaves. The extraction rate was 13.21%, and the dry powder was dissolved and diluted with isotonic 0.9% sodium chloride or ethanol (70%) (standby). Dosage is calculated as mg raw drug/kg body weight. Animals: Male Swiss mice (20-25 g) and male Wistar rats (200-250 g). Anti-inflammatory tests were: 1 Carrageenan-induced foot edema in rats: The extracts were administered orally (250, 500, and 750 mg/kg). Determination of 1,2,3,4, and 5h before and after carrageenan using a volumetric meter
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