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目的:通过对胃间质瘤患者的临床相关资料及文献复习,探讨胃间质瘤的临床表现、辅助检查特征、诊断及治疗方法,以提高对胃间质瘤疾病诊治的认识。探讨胃间质瘤的临床表现、病理特征、诊疗方法及预后。方法:回顾分析本院28例病历完整、经手术治疗和病理组织学确诊的胃间质瘤患者。结果:无明显性别差异,多见50岁以上患者,好发部位胃底、胃体。临床表现无特异性,表现为上腹不适及疼痛22例,上消化道出血16例。超声胃镜、胃镜、消化道钡餐造影或超声及CT可以发现胃间质瘤变,病理组织学及免疫组化检查可确诊。首选手术治疗。行胃楔形切除术15例,胃大部切除术11例。结论:胃间质瘤是独立的胃粘膜下肿瘤,临床表现以消化道慢性不明原因出血、上腹不适和(或)疼痛、腹胀为主。
Objective: To review the clinical data and literature review of patients with gastric stromal tumors to explore the clinical manifestations, auxiliary examination features, diagnosis and treatment of gastric stromal tumors in order to improve awareness of the diagnosis and treatment of gastric stromal tumor. To investigate the clinical manifestations, pathological features, diagnosis and treatment of gastric stromal tumors and prognosis. Methods: A retrospective analysis of our hospital 28 cases of medical history, surgical treatment and pathological diagnosis of gastric stromal tumor patients. Results: no significant gender differences, more common in patients over the age of 50, the site of the stomach, stomach. Clinical manifestations of non-specific, manifested as abdominal discomfort and pain in 22 cases, 16 cases of upper gastrointestinal bleeding. Ultrasound gastroscopy, gastroscopy, gastrointestinal barium meal angiography or ultrasound and CT can be found in gastric stromal tumors, histopathology and immunohistochemistry can be diagnosed. Preferred surgical treatment. 15 cases of gastric wedge resection, partial gastrectomy in 11 cases. Conclusion: Gastric stromal tumor is an independent submucosal tumor. The clinical manifestations include chronic unexplained bleeding in the digestive tract, abdominal discomfort and / or pain and abdominal distension.