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目的:通过经颅多普勒(TCD)检测,了解高原肺水肿(HAPE)患者颅内脑底动脉环上的主要动脉血流动力学及各血流的生理参数,为高原肺水肿的诊断及治疗提供一些参考。方法:将已确诊的HAPE患者,与颞窗通过低频脉冲多普勒(2MHZ),获得颅内脑底动脉环上的主要动脉的多普勒超声频移信号,进行TCD检测。结果:TCD检测后了解到颅内脑底动脉环上的主要动脉:颈内动脉末梢、大脑中动脉、大脑前动脉血流速度(收缩期血流速度,平均血流速度,舒张末期血流速度)与正常人的TCD测值相比明显增快,但舒张末期血流速度(VE)增快较收缩期血流速度(VP)不明显,故频谱仍为低阻波形,搏动指数(PI)、收缩期血流速度与舒张末期血流速度的比值(S/D)正常,阻力指数有所降低。结论:经TCD检测可知高原肺水肿患者在高原(在低氧环境下),颅内主要脑血管扩张,脑血流量增加即颈内动脉系统的MCA,ACA,PICA血流速度(Vs,Vm,Vd)增快,通过TCD检查可为高原医生早期诊断及治疗提供参考。
OBJECTIVE: To understand the main arterial hemodynamics and the physiological parameters of each blood flow in the intracranial cerebral artery rings in patients with high altitude pulmonary edema (HAPE) by transcranial Doppler (TCD) Treatment provides some reference. Methods: The frequency of Doppler ultrasonic signals of the main artery in the cerebral artery rings were obtained by low-frequency pulsed Doppler (2MHZ) and the temporal window of HAPE. The TCD was detected. Results: After TCD examination, the main arteries in the ring of the cerebral artery: the internal carotid artery, the middle cerebral artery and the anterior cerebral artery were observed. The systolic blood flow velocity, systolic blood flow velocity, mean diastolic blood flow velocity, ) Was significantly higher than that of normal people. However, the VE was higher than that of systolic blood flow velocity (Vp), so the spectrum was still low resistance waveform, pulsatility index (PI) , Systolic blood flow and end-diastolic blood flow velocity ratio (S / D) normal, resistance index decreased. Conclusion: TCD examination showed that in patients with high altitude pulmonary edema, the blood flow velocity of MCA, ACA and PICA in the internal carotid artery increased (Vs, Vm, Vd) faster, through the TCD examination for early diagnosis and treatment of plateau doctors provide a reference.