目的观察欣普贝生栓(地诺前列酮栓)在足月妊娠引产中促宫颈成熟的临床效果。方法选择孕周超过40周有临床引产指征单胎孕妇150例,宫颈评分(Bishop)<6分,无妊娠合并症,无阴道分娩禁忌症,无欣普贝生药物使用禁忌症,根据孕妇自愿的原则分为欣普贝生组(观察组)72例及小剂量缩宫素组(对照组)78例,观察组用欣普贝生栓1枚横置于阴道后穹隆,对照组以缩宫素2.5U加入5%葡萄糖液500ml中,以8滴/分钟开始,逐渐加量直到出现规律宫缩。结果观察组第一产程时间、总产程均低于对照组,促宫颈成熟效果较对照组好,引产成功率较对照组高,剖宫产率较对照组低,胎儿评分较对照组高,产后出血量与对照组无统计学差异。结论欣普贝生栓能提高宫颈成熟度促进宫颈成熟提高引产成功率。 Objective To observe the clinical effect of Thinprofecizin (dinoprostone suppository) in promoting cervical ripening in full-term pregnancy induced labor. Methods 150 pregnant women with clinical indications for induction of labor more than 40 weeks gestation were selected. The cervical score (Bishop) was <6, no pregnancy complications, no contraindications to vaginal delivery, no contraindications to drug use by Hinbutaben, The principle of voluntariness was divided into two groups: 72 cases in the Xinpobei group (observation group) and 78 cases in the low-dose oxytocin group (control group). The observation group was treated with Xinpipei suppository and placed in the posterior fornix. The control group Oxytocin 2.5U added 5% glucose solution 500ml, with 8 drops / min start, gradually increase the amount until the regular contractions. Results The duration of the first stage of labor and total length of labor in the observation group were lower than those in the control group. Cervical maturation was more effective than the control group. The success rate of induction of labor was higher than that of the control group. The cesarean section rate was lower than that of the control group. There was no significant difference between the amount of bleeding and the control group. Conclusion Enbubeixi suppository can improve cervical maturation and promote cervical ripening to increase the success rate of induction of labor.