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目的探讨血浆D-二聚体早期诊断急性肠系膜缺血性疾病的方法和临床价值。方法选取30例急性肠系膜缺血性疾病患者作为观察组,选取同期30例健康体检者作为对照组,全部研究对象均行血浆D-二聚体测定,观察其检测结果。结果观察组患者入院第1天、第7天、第10天血浆D-二聚体含量分别为(6.87±2.10)、(3.33±1.20)、(2.33±1.20)mg/L,对照组分别为(0.36±0.06)、(0.36±0.06)、(0.36±0.06)mg/L;观察组患者不同时间血浆D-二聚体含量均显著高于对照组,差异有统计学意义(P<0.05)。血浆D-二聚体进行疾病诊断的敏感度为76.67%(23/30),特异度为80.00%(24/30)。结论对急性肠系膜缺血性疾病患者实施血浆D-二聚体早期诊断可早期筛查疾病,降低患者的死亡率,值得临床进行推广。
Objective To investigate the method and clinical value of early diagnosis of acute mesenteric ischemic disease by plasma D-dimer. Methods Thirty patients with acute mesenteric ischemic disease were selected as the observation group. Thirty healthy subjects were selected as the control group. All the subjects were tested for plasma D-dimer and the results were observed. Results The plasma levels of D-dimer in the observation group were (6.87 ± 2.10), (3.33 ± 1.20) and (2.33 ± 1.20) mg / L on the first day, the seventh day and the tenth day after admission. The control group were (0.36 ± 0.06), (0.36 ± 0.06) and (0.36 ± 0.06) mg / L, respectively. The plasma D-dimer levels in the observation group were significantly higher than those in the control group at different time points (P <0.05) . The diagnostic sensitivity of plasma D-dimer was 76.67% (23/30) and the specificity was 80.00% (24/30). Conclusion Early diagnosis of acute mesenteric ischemic disease in patients with plasma D-dimer early screening of diseases and reduce the mortality of patients, it is worth clinical promotion.