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瑞士种小鼠,按捆束水浸法试验,取饥饿20～22小时后体重在18～21g者,随机分4组,分别ip生理盐水及三七根、叶花总皂甙100mg/kg给药后将各组小鼠固定于特制笼中,浸泡于23±0.2℃的恒温水中,22小时后处死动物、剖检、以胃溃疡斑痕为指标。结果,对照组(n=21)为25.0±9.6,三七根总皂100mg/kg组(n=19)为21.7±6.0,三七总皂甙100mg/kg组(n=19)为15.8±8.8,三七花总皂甙100mg/kg组
The swine strains of mice were immersed in water and immersed for 20 to 22 hours and then weighed between 18 and 21 g. They were randomly divided into 4 groups: ip normal saline, Panax notoginseng and total saponin 100 mg/kg. After that, each group of mice was fixed in a special cage and immersed in a constant temperature water of 23±0.2° C. After 22 hours, the animals were sacrificed, and necropsy was performed, and the signs of gastric ulcer were used as indexes. As a result, the control group (n=21) was 25.0±9.6, the total soap 100 mg/kg group (n=19) was 21.7±6.0, and the total panax notoginseng saponin 100 mg/kg group (n=19) was 15.8±8.8. , Panax notoginseng saponin 100mg/kg group