1973年初,我们在药物广筛中发现一种长效抗疟药磷酸喹哌(代号抗矽—14)对大鼠实验性矽肺具有治疗效果。继后,我们又对磷酸喹哌的给药途径、用药剂量、预防和早期给药、病后早、晚期治疗、停药观察,以及若干生化 In early 1973, we found that a long-acting antimalarial drug, Quipiper (code-named Silicone-14), has been shown to have therapeutic effects on rat experimental silicosis in drug screening. Then, we again on the route of administration of piperazine phosphate, dosage, prevention and early administration, early and late disease treatment, withdrawal observed, and a number of biochemical