论文部分内容阅读
代表Ⅰ.类抗心律失常药的奎尼丁和代表Ⅲ类抗心律失常药的乙胺碘呋酮(以下简称胺碘酮)均可使Q—T间期延长,其结果可引起尖端扭转型室速(TDP),但据笔者使用体会并查阅文献发现胺碘酮引起TDP的机会远远少于奎尼丁,本文就其原因作一些探讨。1 对象与方法1.1 对象:42例心律失常病人分为二组,奎尼丁组20例,胺碘酮组22例,二组间年龄、性别、血电解质均无显著差异。奎尼丁组中风心房颤10例、高心
Quinidine, which represents class I antiarrhythmic drugs, and amiodarone, which represents class III antiarrhythmic drugs (hereinafter referred to simply as amiodarone), prolong the Q-T interval and can result in torsades de pointes (TDP), but according to my experience and access to literature found that amiodarone TDP caused by far fewer opportunities than the quinidine, this article on the reasons for some discussion. 1 Subjects and methods 1.1 Object: 42 cases of arrhythmia patients were divided into two groups, quinidine group 20 cases, amiodarone group 22 cases, between the two groups of age, gender, blood electrolytes were no significant differences. Quinidine group of stroke atrial fibrillation in 10 cases, high heart