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作者使用联合化疗治疗10例难治性免疫性血小板减少症的患者。其中2例是霍奇金病和慢性淋巴细胞白血病所致,其余8例为难治性慢性原发性血小板减少性紫癜。女7例,男3例,中数年龄41.5岁(24~69岁)。血小板减少的时间5~110个月。全部患者的血小板数均<5×10~9/L,除非他们正在接受某种形式的治疗。这些患者既往平均接受过6.8(3~10)种治疗,包括皮质类固醇和脾切除,但均无
The authors used combination chemotherapy in 10 patients with refractory immune thrombocytopenia. Two of them were caused by Hodgkin’s disease and chronic lymphocytic leukemia, and the remaining 8 were refractory chronic thrombocytopenic purpura. 7 females, 3 males, the median age of 41.5 years (24 to 69 years). Thrombocytopenia time of 5 to 110 months. All patients had platelet counts <5x10-9 / L unless they were receiving some form of treatment. These patients had previously received on average 6.8 (3 to 10) treatments including corticosteroids and splenectomy, none of them