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p21WAF1/CIP1(简称p21)是于1993年发现并克隆的细胞周期蛋白依赖性激酶抑制蛋白(CDI)家族成员,参与细胞的多种功能活动。近来发现其与肿瘤发生。发展有关,在肿瘤研究中日益引人注目。1P21的结构与功能P21基因为单拷贝基因,定位于第6号染色体短臂上(即对.2),其DNA长
p21WAF1/CIP1 (abbreviated as p21) is a member of the cyclin-dependent kinase inhibitor (CDI) family discovered and cloned in 1993, and participates in various functional activities of cells. It has recently been found to be associated with tumors. Related to development, it is increasingly attracting attention in cancer research. Structure and Function of 1P21 The P21 gene is a single copy gene and is located on the short arm of chromosome 6 (ie, pair 2), and its DNA is long.