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周期蛋白Ｅｃｙｃｌｉｎ Ｅ与周期蛋白依赖激酶２ＣＤＫ２相结合，参与细胞由Ｇ１期进入Ｓ期，ｃｙｃｌｉｎ Ｅ的过表达可加速其进程。已有大量研究表明ｃｙｃｌｉｎ Ｅ在乳腺癌细胞中有过表达且与预后有密切的关系。细胞周期受电离辐射的调控，并且影响电离辐射的效应
Cyclin E cyclin E and cyclin-dependent kinase 2 CDK2 combined, involved in cell cycle from the G1 phase S, cyclin E overexpression can speed up the process. A large number of studies have shown that overexpression of cyclin E in breast cancer cells and prognosis are closely related. Cell cycle is regulated by ionizing radiation and affects the effects of ionizing radiation