重组人乙酰肝素酶多肽片段的表达与纯化

来源 :军事医学科学院院刊 | 被引量 : 0次 | 上传用户:starrydzf_01
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乙酰肝素酶(heparanase,HPA)是一种内源性β-葡萄糖醛酸酯酶,为迄今发现的唯一作用于细胞外基质多聚糖硫酸乙酰肝素蛋白多糖的内切酶[1].它能够特异性地识别硫酸乙酰肝素(heparan sulfate,HS)结构,并能将其降解为含10~20个糖单位的寡糖链[2,3].
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