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目的探讨脑出血后发生全身炎性反应综合征与患者年龄、性别、出血部位、出血量、血糖的关系。方法全面收集120例急性脑出血患者的临床表现,观察导致全身炎性反应综合征(SIRS)的有关因素并对其进行相关性分析。结果急性脑出血后SIRS的发生与年龄、性别无关;与出血量的大小、是否破入脑室及血糖的高低有显著相关性。并发SIRS及多器官功能障碍综合征(MODS)较不并发SIRS及MODS者病死率明显高。结论急性脑出血患者出现SIRS提示损害仍在进展,病情危重,预后较差,特别是出现MODS时更危重,病死率更高。
Objective To investigate the relationship between systemic inflammatory response syndrome and the patient’s age, gender, bleeding site, blood loss and blood sugar after intracerebral hemorrhage. Methods The clinical manifestations of 120 patients with acute cerebral hemorrhage were collected and the related factors leading to systemic inflammatory response syndrome (SIRS) were observed and analyzed. Results The incidence of SIRS after acute intracerebral hemorrhage was not related to age and gender. It was significantly related to the amount of bleeding, whether it was broken into the ventricle and the level of blood glucose. Concurrent SIRS and multiple organ dysfunction syndrome (MODS) were less complicated with SIRS and MODS mortality was significantly higher. Conclusions SIRS in patients with acute cerebral hemorrhage suggests that the lesions are still undergoing damage, the patients are in critical condition and the prognosis is poor, especially when MODS is more serious and the mortality rate is higher.