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目的比较氧化亚氮联合利多卡因和氧化亚氮单用时在人工流产术中的镇痛作用及软化宫颈等临床效果。方法将320例孕40～70d无阴道分娩史的妇女随机分为氧化亚氮、利多卡因联合镇痛组(观察组)和单用氧化亚氮镇痛组(对照组)各160例。观察组术中吸入氧化亚氮,并于宫颈注射2%利多卡因5ml。对照组仅给予氧化亚氮吸入。结果观察组镇痛效果、软化宫颈与对照组比较,差异均有非常显著性(P<0.01);不良反应发生率无统计学差异(P>0.05)。结论氧化亚氮联合利多卡因用于人工流产术中安全、简便,镇痛效果比单用氧化亚氮更好。
Objective To compare the analgesic effects of nitrous oxide combined with lidocaine and nitrous oxide in artificial abortion and the clinical effect of softening cervix. Methods A total of 320 women with history of vaginal delivery from 40 to 70 days of gestation were randomly divided into two groups: normotensive group (160 cases) with nitrous oxide, lidocaine combined with analgesia group (observation group) and nitrous oxide alone group (control group). Observation group intraoperative nitrous oxide inhalation, and cervical 2% lidocaine injection 5ml. The control group was given only nitrous oxide inhalation. Results The analgesic effect in the observation group was significantly different from that in the control group (P <0.01). The incidence of adverse reactions was not significantly different (P> 0.05). Conclusion The combination of nitrous oxide and lidocaine is safe and easy to use in abortion, and the analgesic effect is better than nitrous oxide alone.