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目的:观察比较沙枣与思密达辅助治疗婴幼儿腹泻的疗效。方法:300例急性非重症腹泻病患儿随机分为两组:A组150例用沙枣干粉剂,B组150例用思密达治疗。结果:治疗72h,A、B两组大便总次数分别减低64.1%和63.3%;每日平均次数较治疗前明显减少(u=9.5,P<0.001),A组水样便由治疗前的72.5%减少至27.5%,脱水患者由75.2%减少为24.8%,与B组结果相近(t=0.74,P=0.4),与治疗前比较差异有统计学意义(u=10.2,P<0.001);每次平均大便量分别减少65.4%和60.0%,差异有统计学意义(t=2.63,P<0.05)。A组和B组每日ORS量分别与治疗初期相比差异有统计学意义(u=10.5,P<0.001),两组间比较差异有统计学意义(t=4.5,P<0.001)。结论:沙枣能减轻腹泻的程度,缩短病程,在减少大便量和ORS的摄入量方面优于思密达。
OBJECTIVE: To observe and compare the therapeutic effects of Radix Scutellariae and Smecta in the treatment of infantile diarrhea. Methods: A total of 300 children with acute non-severe diarrhea were randomly divided into two groups: 150 cases in group A were treated with dry jujube powder, and 150 cases in group B were treated with simvastatin. Results: At 72h after treatment, the total number of stools in groups A and B decreased by 64.1% and 63.3%, respectively. The mean daily number of stools in groups A and B decreased significantly (u = 9.5, P <0.001) (T = 0.74, P = 0.4), and the difference was statistically significant (u = 10.2, P <0.001) before treatment. Each time the average stool volume decreased by 65.4% and 60.0%, the difference was statistically significant (t = 2.63, P <0.05). The daily ORS levels in group A and group B were significantly different from the initial treatment (u = 10.5, P <0.001). There was significant difference between the two groups (t = 4.5, P <0.001). Conclusion: The jujube can reduce the degree of diarrhea and shorten the course of the disease, and is superior to Smecta in reducing the amount of stool and ORS intake.