慢性阻塞性肺疾病(慢阻肺)急性加重是慢阻肺患者发病和死亡的主要原因,急性加重的定义为出现呼吸困难加重,痰量增多,或出现脓性痰并可伴低氧血症和高碳酸症。胃食管反流病(GERD)是一种常见的食管疾病,胃内容物微吸入和胃酸刺激食管引起迷走神经介导的支气管痉挛,上述原因可促成GERD与慢阻肺症状之间的联系,抗反流治疗有利于慢阻肺的控制和缓解,且可减少慢阻肺的 Acute exacerbation of chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality in COPD patients. Acute exacerbations are defined as the presence of worsening dyspnea, increased sputum volume, or purulent sputum with hypoxemia And hypercapnia. Gastroesophageal reflux disease (GERD) is a common esophageal disease, microinvasive inhalation of gastric contents, and gastric acid-stimulated esophageal vagal-mediated bronchospasm. These causes contribute to the link between GERD and COPD, Flow therapy is conducive to the control and remission of COPD, and can reduce COPD