作者报告1974年7月到1976年10月18例经活检证实的限局或区域性、不能切除的胰腺癌,给予高剂量、小体积放射治疗的结果。区域性病灶是指病灶虽已出胰腺范围,但无肝受累或超出上腹部的播散。病人诊断时平均年龄60.7岁(40～82岁)。男15例,女8例。最常见的症状是黄疸(83%),疼痛(72%),体重减轻(61%),食欲不振(50%)和恶心(33%)。2例近期出现糖尿病。全部病例都作了开腹探查,同时活检,并用不透放射线的夹子标出肿瘤范围。通常作了短路手术。病理诊断均为导管腺癌。治疗前的实验室检查有CEA、上消化道造影等。每例均作静脉肾盂造影,用交叉定 The authors reported the results of high-dose, small-volume radiation therapy in 18 cases of limited- or regionally unresectable pancreatic cancer confirmed by biopsy between July 1974 and October 1976. Regional lesions means that although the lesion has been out of the pancreas, there is no liver involvement or spread beyond the upper abdomen. The average age at diagnosis was 60.7 years (40-82 years old). There were 15 males and 8 females. The most common symptoms were jaundice (83%), pain (72%), weight loss (61%), loss of appetite (50%), and nausea (33%). Two cases of diabetes occurred recently. In all cases, laparotomy was performed, biopsy was performed, and the tumor range was marked with a radiographic clip. Short-circuit surgery is usually performed. Pathological diagnosis was ductal adenocarcinoma. Pre-treatment laboratory tests include CEA and upper gastrointestinal angiography. In each case, an intravenous pyelogram was used for imaging.