自1971年Shafer首次报告15例疣状黄色瘤以来,至今文献共报告50例(包括本文21例)。本组21例中,临床诊断为乳头状瘤7例,其它诊断有癌,角化病以及炎症性疾患。病变存在时间自3周到7年,呈“白色疣状”或“红色溃疡状”,病变大小为0.15～2cm。本组的年龄、病变位置及种族与文献报告的29例很相似。女与男之比为2∶1,而以前报告男女相等。结合以前报告的病例,其结果如下:年龄18～80岁,平均48岁,主要在 Since Shafer first reported 15 cases of verrucous xanthoma in 1971, a total of 50 cases (including 21 cases in this article) have been reported in the literature to date. Of the 21 patients in this group, 7 were clinically diagnosed as papilloma and other diagnoses were cancer, keratoses, and inflammatory disorders. The lesions lasted from 3 weeks to 7 years and showed a “white wart-like” or “red ulcer-like” lesion size of 0.15 to 2 cm. The age, location, and race of this group are very similar to those reported in 29 cases. The ratio of women to men is 2:1, while men and women were previously reported to be equal. Combined with previously reported cases, the results are as follows: Age 18-80 years old, average 48 years old, mainly in