目的:探讨乳腺纤维腺瘤并乳腺癌的临床病理特点及影像学特征。方法:对2007年～2008年病理诊断为乳腺纤维腺瘤病例进行回顾性研究,对其中乳腺非典型增生及恶变的乳腺纤维腺瘤、乳腺纤维腺瘤并乳腺癌的41例病例进行病理组织学和超声影像分析。结果:超声影像诊断分三种:1.乳腺纤维腺瘤;2.乳腺纤维腺瘤,乳腺癌待排;3.乳腺癌。病理诊断结果3708例乳腺纤维腺瘤中,伴有导管上皮非典型增生及原位癌12例(12/3708),伴有导管上皮非典型增生-小管癌1例(1/3708),乳腺纤维腺瘤及乳腺癌29例(29/3708)。结论:乳腺纤维腺瘤可发生恶变,也可与乳腺癌并发,体检及超声检查均不易检出。体检、超声和病理综合检查是避免漏诊的关键。 Objective: To investigate the clinicopathological characteristics and imaging features of breast fibroadenoma and breast cancer. Methods: The pathological diagnosis of breast fibroadenoma cases from 2007 to 2008 were retrospectively studied. Pathological histology was performed in 41 cases of atypical hyperplasia and malignant breast fibroadenoma, breast fibroadenoma and breast cancer And ultrasound image analysis. Results: Ultrasound imaging is divided into three types: 1. Breast fibroadenoma; 2. Breast fibroadenoma, breast cancer to be discharged; 3. Breast cancer. Pathological diagnosis of 3,708 cases of breast fibroadenoma, associated with atypical hyperplasia of ductal epithelium and carcinoma in situ in 12 cases (12/3708), accompanied by atypical hyperplasia of ductal epithelium - 1 case of ductal carcinoma (1/3708), breast fibroadenoma Adenoma and breast cancer in 29 cases (29/3708). Conclusion: Malignant breast fibroadenoma may occur, but also with breast cancer, physical examination and ultrasound are not easy to detect. Physical examination, ultrasound and pathological examination is the key to avoid misdiagnosis.