Wegener肉芽肿是一种原因未明、多系统受累的非特异性肉芽肿病。临床表现上、下呼吸道和肾脏病变三联征,和/或伴有全身性广泛性肉芽肿性血管炎者,称全身型;病变局限于上、下呼吸道者,称局限型。本文报告全身型Wegener肉芽肿3例,并对本病的肺部表现和诊断加以讨论。 Wegener’s granulomatosis is a nonspecific granulomatous disease of unknown origin and multiple systemic involvement. Clinical manifestations, lower respiratory tract and nephropathy triad, and / or associated with generalized granulomatous vasculitis who, said the whole body; lesions limited to the upper and lower respiratory tract, said localized. This article reports three cases of systemic Wegener’s granulomatosis and discusses the pulmonary manifestations and diagnosis of the disease.