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目的 :探讨肾结石与血、尿生化指标的关系。方法 :随机抽取深圳市宝安区 187名肾结石病例和 4 4 7名对照进行病例对照研究 ,采用 t检验、趋势卡方检验等分析血、尿生化指标与肾结石的关系。结果 :血尿素氮病例组高于对照组(t=3.2 0 9,P=0 .0 0 1) ;尿镁 (t=- 1.75 9,P=0 .0 79)、血镁 (t=- 0 .32 9,P=0 .74 2 )病例组低于对照组 ,趋势卡方 (P= 0 .0 0 3)检验显示血尿素氮浓度与肾结石患病危险度成正比。结论 :血尿素氮是肾结石危险因素 ,尿镁、血镁是肾结石的保护因素。
Objective: To investigate the relationship between kidney stones and biochemical indexes of blood and urine. Methods: A total of 187 kidney stones and 477 controls were randomly selected from Bao’an District of Shenzhen City for case control study. The relationship between serum and urine biochemical markers and renal calculi was analyzed by t test and trend chi square test. Results: Compared with the control group, the levels of blood urea nitrogen (t = - 1.759, P = 0.079) 0 .32 9, P = 0.74 2) The case group was lower than the control group. The trend chi-square test (P = 0.0000) showed that the concentration of blood urea nitrogen was directly proportional to the risk of kidney stones. Conclusion: Blood urea nitrogen is a risk factor of kidney stones. Urinary magnesium and blood magnesium are the protective factors of kidney stones.