宫颈上皮内瘤变是浸润性宫颈癌的癌前病变,由于发病年龄年轻化,治疗多采用保留生育功能的宫颈锥切术,但术后有较高复发率,其原因可能有生物学因素,如HPV病毒和HIV病毒感染、锥切术标本切缘阳性和切缘细胞核变化、宫颈腺体受累、巨噬细胞浸润、行为因素如吸烟及患者年龄等。 Cervical intraepithelial neoplasia is invasive precancerous lesions of cervical cancer, due to the age of onset, treatment and more use of reproductive function of cervical conization, but a higher recurrence rate after surgery, the reasons may be biological factors, Such as HPV and HIV infection, conization specimens of positive and marginal cutting edge of nuclear changes, cervical gland involvement, macrophage infiltration, behavioral factors such as smoking and patient age.