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1 功效与剂量表现为正相关功效与剂量成正比关系:“有效量——中毒量——致死量。”在一定范围内,同一药物随着剂量的递增,药物效应也相应增加。生物体表现出不同的效应指标,这种剂量与效应的关系叫量效关系。这是一条普遍的规律,在临床药理和实验药理中都得到了普遍的证实。无论中药、西药大率如此。如:口服东莨菪碱0.65mg可使精神活动减弱;2.0mg可引起健忘;4.5mg则发生幻觉、定向障碍;肌注5mg—50mg可导致昏迷。另如:知母浸膏,中性原液总静脉注射0.
1 Efficacy and dose performance are positively related to efficacy and dose proportional relationship: “effective amount - amount of poisoning - lethal dose.” Within a certain range, the same drug with increasing dose, the drug effect also increased. Organisms exhibit different effect indicators. The relationship between dose and effect is called dose-effect relationship. This is a universal law that has been widely confirmed in clinical pharmacology and experimental pharmacology. Regardless of the Chinese medicine, Western medicine rate so. Such as: oral scopolamine 0.65mg can make mental activity weaken; 2.0mg can cause forgetfulness; 4.5mg hallucinations, disorientation; intramuscular injection of 5mg -50mg can lead to coma. Another example: Anemarrhena extract, a total intravenous injection of neutral stock solution