乙型肝炎病毒(HBV)的复制是以其RNA为中间体,通过反转录酶的作用而进行的,可能由于缺乏校读的功能,因此,与大多数DNA病毒相比,HBV具有较高的突变率,故了解其变化特点十分重要。现就HBV不同的基因型与病毒变异及临床的关系,不同基因位点变异的临床意义以及中医辨证论治研究概况介绍如下。 Hepatitis B virus (HBV) replication is based on its RNA as an intermediate, by the action of reverse transcriptase, probably due to the lack of proofreading functions, and therefore HBV has a higher level of HBV than most DNA viruses Of the mutation rate, it is important to understand the changing characteristics. Now different HBV genotypes and viral mutations and clinical relations, clinical significance of different genetic loci variation and TCM syndrome differentiation research overview is as follows.