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胃癌是全球常见恶性肿瘤之一,其临床治疗效果仍差强人意。2020年,高质量的临床研究结果不断涌现,给临床诊疗的新理念和新方式提供了循证医学证据。外科手术、围手术期治疗和免疫治疗等多个方面的研究结果,胃癌手术方式改变、围手术期化疗方案改进和免疫与化疗的代替与结合,都为胃癌临床疗效的进一步提高提供了可能。胃肠外科医师在临床实践过程中需结合当前研究进展、为不同患者制定个体化的综合治疗方案,有望进一步改善患者预后和生活质量。“,”Gastric cancer is a common type of malignant tumors, but its clinical prognosis remains unsatisfactory. Up to 2020, a growing number of high-quality clinical researches has provided reliable evidence for clinical practice. Evidences from surgery, perioperative treatment and immunotherapy, such as changes in surgical methods, improvement of perioperative chemotherapy and combination of immune and chemotherapy strategy, provided the possibility to improve the clinical efficacy of gastric cancer. In our clinical practice, gastrointestinal surgeons need to integrate the current research progression and develop individualized strategy for different patients, which is expected to further improve the prognosis and quality of life for patients with gastric cancer.