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6月12日,中国水稻研究所王克剑课题组和中国科学院遗传与发育生物学研究所李家洋课题组合作开展的研究结果在线发表于《植物生物技术杂志(Plant Biotechnology Journal)》上。该研究显著提高了CRISPR-Cas9-VQR系统在水稻中的基因组编辑效率。CRISPR-Cas9系统已经广泛应用于基因组编辑。但是该系统在进行基因组编辑时,除需要特异识别靶序列之外,还需要特异识别一段NGG的邻近
On June 12, Wang Kejian’s team from China National Rice Research Institute and Li Jiayang’s research group at the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, jointly published the findings in “Plant Biotechnology Journal”. This study significantly improved the genomic editing efficiency of CRISPR-Cas9-VQR system in rice. CRISPR-Cas9 system has been widely used in genome editing. However, in the genome editing, the system needs to specifically recognize the adjacent NGG in addition to the need to specifically recognize the target sequence